Cancer

Cancer Vaccine Proves 100% Success In Mice

cancer-vaccine-proves-100-success-mice

Scientists have developed a new vaccine that — in conjunction with existing therapies — can not only treat aggressive melanoma, but also prevent its recurrence.

Researchers from the Scripps Research Institute in San Diego, CA, recently worked with experts from other institutions to develop a vaccine that would be effective against melanoma (a type of skin cancer) when administered in conjunction with other therapies.

According to Prof. Dale Boger, who co-led the research with Nobel laureate Bruce Beutler, “This co-therapy produced a complete response — a curative response — in the treatment of melanoma.”

These promising results are reported in a study paper now published in the journal PNAS.

Experimental approach fully successful

The researchers tested three different therapy options in a mouse model of aggressive melanoma. All of the mice received a type of cancer immunotherapy known as anti-PD-L1, but in addition to this, they also received different vaccine variants.

Prof. Boger and team split the mice into three groups: one group had the cancer vaccine, another group had the vaccine plus a molecule called Diprovocim, and the third group had the cancer vaccine and another adjuvant: a chemical known as alum.

source: medicalnewstoday.com

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